Palmitic Acid-Enriched Diet Induces Hepatic Steatosis and Injury in Adult Zebrafish
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چکیده
منابع مشابه
E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish
BACKGROUND Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the development of metabolic syndrome. While advanced stage nonalcoholic hepatic steatosis and steatohepatitis (NASH) result ultimately in fibrosis and cirrhosis, the molecular basis for lipid droplet formation is poorly understood. Common pathways underlie the pathology of ...
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The consumption of diets rich in saturated fat largely contributes to the development of obesity in modern societies. A diet high in saturated fats can induce inflammation and impair leptin signaling in the hypothalamus. However, the role of saturated fatty acids on hypothalamic leptin signaling, and hepatic glucose and lipid metabolism remains largely undiscovered. In this study, we investigat...
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ژورنال
عنوان ژورنال: Zebrafish
سال: 2019
ISSN: 1545-8547,1557-8542
DOI: 10.1089/zeb.2019.1758